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We are thinking of buying a dynamic/static light scattering unit to analyze our samples. The Nanostar from Wyatt (previously from Dynapro) seems to combine both DLS and static light scattering. I was wondering if anyone has experience with it? How good/accurate are the static light scattering measurements compared to the 18-angle Heleos or 3-angle Treos? It looks like the instrument is primarily designed for DLS, so I was wondering how bad the static scattering detector is. We are primarily interested in getting an estimation for absolute MWs, and we would like to have temperature control, which the Heleos seems to lack...

Thank you so much.

Alex

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We have an 18-angle Dawn EOS (quite old) from Wyatt. It does static and dynamic light scattering, in either batch (cuvette) or flow mode, with temperature control. It seems to do everything we need, though I am by no means a sophisticated user. I've never used the other instruments that you mention. For what it's worth, Wyatt's customer service seems to be quite good.

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